Welcome!
Thank you for visiting our laboratory’s website and exploring our research activities, scientific contributions, and publications.
Our research integrates cellular and molecular biology with quantitative morphology, focusing on the interactions among nutrition, metabolism, obesity, diabetes, and pharmacological interventions. We emphasize morphometry, stereology, and allometry, combining structural, molecular, and functional approaches to advance our understanding of health and disease.
Our scientific publications are available in the final section of this website, organized chronologically by year. Each publication includes a DOI link providing direct access to the article on the publisher’s website, where the full text may be downloaded when available.
Below is a selection of review articles that provide an overview of our principal research areas. These resources are intended for students, researchers, healthcare professionals, and other visitors interested in biomedical sciences.
Some free-access reviews.
- Mandarim-de-Lacerda CA. Stereological tools in biomedical research. Ann Braz Acad Sci 2003;75:469-86 (doi: 10.1590/S0001-37652003000400006).
- Mandarim-de-Lacerda CA, Del Sol M. Tips for studies with quantitative morphology (morphometry and stereology). Int J Morphol 2017;35:1482-94 (doi: 4067/S0717-95022017000401482)
- Mandarim-de-Lacerda, CA. Ontogenetic and phylogenetic allometry (bivariate and multivariate) for young morphologists. Int J Morphol 2019;37(2):466-472 (doi: 10.4067/S0717-95022019000200466)
- Mandarim-de-Lacerda, CA. Pancreatic islet (of Langerhans) revisited. Histology and Histopathology 2019;34:985-993 (doi: 10.14670/HH-18-118)
- Aguila MB, Ornellas F, Mandarim-de-Lacerda CA. Nutritional research and fetal programming: parental nutrition influences the structure and function of the organs. Int J Morphol 2021;39:327-334 (doi: 10.4067/S0717-95022021000100327)
- Mandarim-de-Lacerda CA, Del Sol M, Vasquez B, Aguila MB. Mice as an animal model for the study of adipose tissue and obesity. Int J Morphol 2021;39:1521-1528 (doi: 10.4067/S0717-95022021000601521)
- Mandarim-de-Lacerda CA. The morphological challenge in determining nuclear size and shape in anatomopathological neoplasia analysis. Int J Morphol 2022;40:683-7 (doi: 10.4067/S0717-95022022000300683)
- Spezani R, Reis-Barbosa P, Mandarim-de-Lacerda CA. Update on the transdifferentiation of pancreatic cells into functional beta cells for treating diabetes. Life Sciences, 2024:122645 (doi:10.1016/j.lfs.2024.122645)
- Fabiano MM, Aguila MB, Mandarim-de-Lacerda CA. The Hypothalamus and Hippocampus are Targets for New Drugs Controlling the Energy Balance and Treating Type 2 Diabetes Mellitus, Obesity, and Neurodegenerative Diseases. Int J Morphol 2025;43(1):182-193 (doi: 10.4067/S0717-95022025000100182).
- Mandarim-de-Lacerda CA. Two millennia of anatomical discovery: shaping the evolution of medicine. Int J Morphol 2025;43(3): 891-900 (doi: 10.4067/S0717-95022025000300891)
- Mandarim-de-Lacerda CA. From Encephalization to Bipedalism: Lessons from Human
Evolution for Contemporary Health. Anais da Acad Nac Medicina 2025;196(3):52-67 (doi: 10.52130/27639878-AANM2025v196n3p52-67)
- Spezani R, Mandarim-de-Lacerda CA. Beyond Diabetes and Obesity: GLP-1 Receptor Agonists in Disrupting the Vicious Cycle of Metabolic Dysfunction and Neuroinflammation. Diabetes Obes Metab. 2026;28:1622-1637 (doi:10.1111/dom.70400)
- Bittencourt JOA, Giannini JF, Guarnieri RS, Marinho TS, Penna-de-Carvalho A, Reis-Barbosa PH, Aguila MB, Mandarim-de-Lacerda CA. Neuroinflammation as a Central Axis in Brain Aging and Neurodegenerative Diseases: Mechanisms, Functional Consequences, and Therapeutic Perspectives. Anais Acad Nac Med 2026; 197: 11-27 (doi:10.52130/27639878-AANM2026v197n1p11-27)
- Marcondes-de-Castro IA, Sales TA, Marinho TS, Aguila MB, Mandarim-de-Lacerda CA. Redox-sensitive coordination of mitochondrial quality control: Integrating ROS, NAD(+), and Ca(2+) signaling in disease. Life Sci 2026;403:124642, doi:10.1016/j.lfs.2026.124642.
- Mandarim-de-Lacerda CA. A Socratic-Platonic dialogue on quantitative morphology and stereological inference. Int J Morphol 2026;44(3):829-841 (doi: 10.4067/s0717-95022026000300829)

Abbreviated CV
Carlos Alberto Mandarim-de-Lacerda graduated in Medicine from the State University of Rio de Janeiro (UERJ, 1978), earned a Master of Science degree from the Federal University of Rio de Janeiro (UFRJ, 1981), and obtained his Doctorate in Human Biology (Docteur d’État, Biologie Humaine) from Université Paris Cité (1985; formerly Université Paris V), where he also completed postdoctoral training between 1989 and 1990. His international researcher identifiers are ORCID (0000-0003-4134-7978) and ResearcherID (P-2360-2019).
He has been a Full Professor at UERJ’s Institute of Biology since 1988. He founded the Department of Anatomy and served multiple terms as Department Chair beginning in 1986. He currently coordinates the Graduate Program in Human and Experimental Biology (PPGBHEx) and leads a CNPq Research Group focused on Nutrition, Obesity, Metabolism, Chronic Diseases, and Pharmacological Therapies.
His academic career has been recognized through several national and international distinctions. He has been a Full Member of the Brazilian National Academy of Medicine (Chair No. 82) since 2011, an Honorary Professor at the Faculty of Medicine of Universidad de La Frontera, Chile, since 2013, and a Foreign Associate Member of the French National Academy of Medicine (Académie Nationale de Médecine) since 2018.
Throughout his career, he has maintained sustained scientific productivity, accompanied by increasing bibliometric impact and international recognition. In 2020, he was included among the world’s 100,000 most influential scientists and the 600 most influential Brazilian researchers, according to a study published in PLOS Biology. The continuity of this scientific trajectory is further supported by the August 2026 update of the Updated Science-Wide Author Databases of Standardized Citation Indicators (Elsevier/Mendeley Data), compiled by John P. A. Ioannidis. Based on Scopus data through 2025 and the composite citation score (c-score), excluding self-citations, he ranks first among researchers affiliated with UERJ, 175th among the 1,304 Brazil-affiliated researchers identified in the database, and 69,835th worldwide, within the Anatomy & Morphology subfield of Clinical Medicine, with 368 publications indexed in the database.
The sustained scientific productivity is also reflected in the AD Scientific Index 2026, which reports a career h-index of 64 and an i10-index of 272, indicating that at least 64 publications have each received 64 or more citations, while 272 publications have received at least 10 citations each. For the most recent five-year period, the corresponding h-index and i10-index are 38 and 146, respectively, highlighting the substantial contribution of recent publications to his overall scientific impact. In the international ranking for Anatomy, he ranks 37th worldwide.
Taken together, his sustained publication record, the substantial impact of his recent research, and his recognition in successive international assessments demonstrate consistent scientific productivity and the progressive consolidation of his academic influence. These achievements reflect his contributions to advancing Morphological and Biomedical Sciences, as well as his institutional leadership and longstanding commitment to graduate education and researcher training.
References
- Ioannidis JPA, Boyack KW, Baas J. Updated science-wide author databases of standardized citation indicators. PLOS Biology. 2020;18(10). https://doi.org/10.1371/journal.pbio.3000918.
- Ioannidis JPA. August 2026 data-update for “Updated science-wide author databases of standardized citation indicators” [dataset]. Version 9. Mendeley Data; 2026. https://doi.org/10.17632/btchxktzyw.9.
- AD Scientific Index. Carlos Alberto Mandarim-de-Lacerda — Scientist Profile. World Scientist Rankings 2026. Available at: https://adscientificindex.com/scientist/carlos-alberto-mandarim-de-lacerda/887373. Accessed October 13, 2026.
Welcome
/in Posts /by AdminWelcome!
Thank you for visiting our laboratory’s website and exploring our research activities, scientific contributions, and publications.
Our research integrates cellular and molecular biology with quantitative morphology, focusing on the interactions among nutrition, metabolism, obesity, diabetes, and pharmacological interventions. We emphasize morphometry, stereology, and allometry, combining structural, molecular, and functional approaches to advance our understanding of health and disease.
Our scientific publications are available in the final section of this website, organized chronologically by year. Each publication includes a DOI link providing direct access to the article on the publisher’s website, where the full text may be downloaded when available.
Below is a selection of review articles that provide an overview of our principal research areas. These resources are intended for students, researchers, healthcare professionals, and other visitors interested in biomedical sciences.
Some free-access reviews.
Evolution for Contemporary Health. Anais da Acad Nac Medicina 2025;196(3):52-67 (doi: 10.52130/27639878-AANM2025v196n3p52-67)
Abbreviated CV
Carlos Alberto Mandarim-de-Lacerda graduated in Medicine from the State University of Rio de Janeiro (UERJ, 1978), earned a Master of Science degree from the Federal University of Rio de Janeiro (UFRJ, 1981), and obtained his Doctorate in Human Biology (Docteur d’État, Biologie Humaine) from Université Paris Cité (1985; formerly Université Paris V), where he also completed postdoctoral training between 1989 and 1990. His international researcher identifiers are ORCID (0000-0003-4134-7978) and ResearcherID (P-2360-2019).
He has been a Full Professor at UERJ’s Institute of Biology since 1988. He founded the Department of Anatomy and served multiple terms as Department Chair beginning in 1986. He currently coordinates the Graduate Program in Human and Experimental Biology (PPGBHEx) and leads a CNPq Research Group focused on Nutrition, Obesity, Metabolism, Chronic Diseases, and Pharmacological Therapies.
His academic career has been recognized through several national and international distinctions. He has been a Full Member of the Brazilian National Academy of Medicine (Chair No. 82) since 2011, an Honorary Professor at the Faculty of Medicine of Universidad de La Frontera, Chile, since 2013, and a Foreign Associate Member of the French National Academy of Medicine (Académie Nationale de Médecine) since 2018.
Throughout his career, he has maintained sustained scientific productivity, accompanied by increasing bibliometric impact and international recognition. In 2020, he was included among the world’s 100,000 most influential scientists and the 600 most influential Brazilian researchers, according to a study published in PLOS Biology. The continuity of this scientific trajectory is further supported by the August 2026 update of the Updated Science-Wide Author Databases of Standardized Citation Indicators (Elsevier/Mendeley Data), compiled by John P. A. Ioannidis. Based on Scopus data through 2025 and the composite citation score (c-score), excluding self-citations, he ranks first among researchers affiliated with UERJ, 175th among the 1,304 Brazil-affiliated researchers identified in the database, and 69,835th worldwide, within the Anatomy & Morphology subfield of Clinical Medicine, with 368 publications indexed in the database.
The sustained scientific productivity is also reflected in the AD Scientific Index 2026, which reports a career h-index of 64 and an i10-index of 272, indicating that at least 64 publications have each received 64 or more citations, while 272 publications have received at least 10 citations each. For the most recent five-year period, the corresponding h-index and i10-index are 38 and 146, respectively, highlighting the substantial contribution of recent publications to his overall scientific impact. In the international ranking for Anatomy, he ranks 37th worldwide.
Taken together, his sustained publication record, the substantial impact of his recent research, and his recognition in successive international assessments demonstrate consistent scientific productivity and the progressive consolidation of his academic influence. These achievements reflect his contributions to advancing Morphological and Biomedical Sciences, as well as his institutional leadership and longstanding commitment to graduate education and researcher training.
References
End year lunch
/in Posts /by Carlos Alberto Mandarim-de-Lacerda